Cannabis contains more than 100 cannabinoids, but there are two main ones, which have very different effects and legal status. These are THC (Tetrahydrocannabinol) and CBD (Cannabidiol). Each one produces something different, and contributes both to the sensation produced by marijuana and to its therapeutic applications. Knowing both compounds allows you to make a better choice of strain when growing, as well as knowing what to look for depending on whether you want something recreational or medicinal.

First, what they have in common: both TCH and CBD are cannabinoids, and act on the endocannabinoid system, which all mammals, including humans, have. This is an intercellular communication system, which is naturally activated to create homeostasis, but can be stimulated by phytocannabinoids, that is, cannabinoids of plant origin, such as those found in the marijuana plant. These cause different effects than those that occur naturally in the body. The main receptors of the endocannabinoid system are CB-1 and CB-2, which are found in the central nervous and immune systems.

THC is the psychoactive component of cannabis, and it binds to these two receptors in the human brain. CB-1 influences pleasure, appetite, memory and concentration, while CB-2 moderates the sensation of pain, and plays a role in homeostasis in certain parts of the body, such as the kidney and liver.

In addition, THC is the component responsible for making you want to eat a pizza and go to sleep after smoking a joint. It increases appetite and increases the feeling of pleasure when eating, as well as producing drowsiness. This is why it is used in treatments for insomnia and loss of appetite. It is also THC that affects short-term memory, so blame it too the next time you say «what was I talking about?» in the middle of a conversation when you are stoned. In general, the strains with the highest THC are the most sought after for recreational use. It is also the component mostly banned or restricted by most countries around the world.

CBD, on the other hand, interacts with receptors such as GPR55 or 5-HT1A. It is not psychoactive, although it works in many ways with THC to contribute to the effect of cannabis. In fact, it counteracts the effects of THC in several ways, so its ratio is important in determining the sensation produced by marijuana. CBD reduces the anxious feeling characteristically caused by THC, and has antipsychotic properties that balance the stronger effects of the high. It is also associated with wakefulness and energy, so it also complements THC, although if a sedative effect is sought, it is best if the proportion of CBD is low. As for memory, it also reduces the impairment caused by THC, so low-CBD strains are the ones that will leave you wondering where you left the keys you actually have in your hand.

CBD is also the most sought after component in strains for medicinal use. It has anti-inflammatory properties far superior to THC and without the psychotropic effects, making it safe for any patient. It is widely used in afflictions such as arthritis and rheumatism. CBD also has an anticonvulsant effect and reduces muscle spasms, which is why it is often prescribed for refractory epilepsy. It is also anxiolytic and antipsychotic, with studies supporting its use in the treatment of schizophrenia.

Both cannabinoids play important roles and work perfectly together, regulating each other, although depending on the effect and desired use, varieties richer in one or the other compound will be chosen. If you suffer from any disease or have had a tremendous blow, you may want a lot of CBD, but if your plan is to watch a movie and finish just a bag of potato chips, THC is your thing. Just remember that without a good balance of CBD, you may never finish the movie because you fall asleep, or forget what it was about in the first place. The right balance is the secret. And if you want to buy THC Austin, remember that it is completely legal.

What is Delta-8-THC?

Delta-8-THC is a cannabinoid similar to Delta-9-THC, but is generally considered less potent. Many Delta-8-THC users report that the cannabinoid gives them a floating, weightless feeling similar to other cannabis products, but with less brain fog.

Delta-8 THC vs. Delta-9 THC: What’s the difference?

Delta-9-tetrahydrocannabinol and Delta-8-THC are almost identical in structure and have similar psychoactive effects. Delta-9 and Delta-8 are similar in that both cannabinoids bind to the same cannabinoid receptors in the human nervous system.

The relatively obscure Delta-8-THC and the very popular Delta-9-THC molecules are little more than two atoms apart. Delta-8-tetrahydrocannabinol appears to have similar therapeutic efficacy to Delta-9-THC.

However, a key difference is that Delta-8-THC is one of a dozen minor cannabinoids, while Delta-9-THC is a primary cannabinoid. Delta-8-THC appears in very mild concentrations in the cannabis plant, but this relatively scarce cannabinoid is on its way to becoming one of the most popular elements of the plant.

How Delta-8 THC affects the body

One of the reasons for the rise in popularity of Delta-8-THC is that it is nowhere near as psychoactive as Delta-9-THC, the cannabinoid that notoriously «gets you high.» The National Cancer Institute agrees that Delta-8-THC will leave medical cannabis patients with a milder psychoactive footprint, concluding, «This agent exhibits lower psychotropic potency than Delta-9-tetrahydrocannabinol (Delta-9-THC), the primary form of THC found in cannabis.»

These properties make Delta-8 THC potentially very useful for children, people especially sensitive to Delta-9 THC, and those looking for something more tolerable to relieve chronic pain during the day. However, these potential therapeutic effects apply more to naturally occurring delta-8-THC, not the synthesized version that is made by transforming CBD.

Health Benefits and Uses

Delta-8-THC offers many of the same potential therapeutic benefits as delta-9-THC, if we are referring to the non-synthesized version. Here are some therapeutic purposes of delta-8-THC:

Pain relief

THC serves a dual function in reducing pain and related inflammation. Different forms of the cannabinoid can even help with difficult-to-treat and intense pain associated with chronic conditions such as multiple sclerosis (MS) and cancer treatments such as chemotherapy.

Digestive Benefits

Delta-8-THC may stimulate appetite while reducing nausea and vomiting in some people. However, there is more evidence for Delta-9-THC’s ability to help with digestive disorders.

Relaxation

Calming mild anxiety is one of the main reasons people turn to Delta-8-THC. The cannabinoid provides a natural alternative to prescription anxiety medications, but you should consult your medical professional first.

 

Scientists succeed in sequencing RNA remnants of a 1918 influenza virus strain

The lungs of young German soldiers, which appeared on June 27, 1918, are housed in the Berlin History Museum in Germany. The deceased young men were between 18 and 17 years old and died from a strain of influenza virus that emerged at the beginning of the year mentioned above.

However, researchers have followed up on parts of what infected the two young men. Science Mag is still analyzing these two and other human genomes that died from the virus. On the other hand, Henrik Poinar directs compliments to the creators of this finding, being a former head of the McMaster University DNA lab.

There are remains of the deceased that have been studied, including the remains of the two soldiers mentioned above and one woman, which are spread out in the Medical Museum in Berlin and in a collection in Vienna in Austria.

RNA sequencing Spain (in spanish: secuenciación ARN España) continues with much more advanced examinations of all the studies that have been done previously. It is hard work, but the technology has allowed the virus strain to be investigated more thoroughly and effectively.

Is it an impossible task?

Among the studies carried out, the presence of the flu virus among the three deceased is revealed in the RNA fragments. RNA Laboratories Spain (Laboratorios ARN España) notes that it happens with SARS-CoV-2, better known as Covid-19, being a genome composed of RNA, and not DNA.

The decomposition of those fragments has been inevitable, but the researchers managed to reconstruct the remains of the woman mentioned above. It may be curious that these three deceased are part of the research, since they were related according to their genetic material.

The RNA remains found in the woman match 90% and 60% with each of the men also deceased. Calvignac-Spencer has assured that the work is not impossible, due to the fact that, to sequence the genetic material with formalin-fixed tissue is much more difficult in this type of samples than in others.

We must highlight the great work of Calvignac-Spencer, for managing to materialize what many scientists have called a «feat», being a clear example of some hidden data that can provide valuable information about the 1918 pandemic.

Having information about previous strains is crucial to understand and prevent the current consequences. Taking into account that technology and science are great allies for researchers in charge of this work, in ancient times diseases were very unknown compared to today.

The professionals, by taking better samples of the 1918 influenza virus strain from fragments of deceased people that rest in institutions as valuable objects related to science.

Can the two pandemics be linked?

As mentioned above, identifying a virus in that year was very difficult, due to the limited resources we have today. Although the virus was detected in 1918, it was actually known that it was in 1933, since there was no knowledge or possibility of developing vaccines.

The 1918 flu is considered the worst catastrophe at that time, when the continent was at war and a pandemic killed many sick people. Years later, when the world was at peace again, studies on this event were reinforced.

The onset of the current pandemic by Covid-19, it is inevitable not to look back to the popular Spanish flu of 1918. Looking for similarities has prevented the worst episodes from repeating themselves, thanks to technology, science and the internet we have greater access to history and studies by professionals.

By understanding certain similarities of contagion, it is possible to understand what is happening today and prevent its spread. The combination of World War I, economic crisis and terrible pandemic, it is possible to associate today.

As a difference, and advantage, at present, is the possible reinforcement of sanitary measures around the world, taking into account economic inequalities to improve or not worsen the living and working conditions of each person. What was not possible in 1918 with the pandemic.

 

The bible in audio in Spanish

The bible is the most important text for religious believers, it is a compilation of sacred books where the stories, doctrines, traditions and codes that guide religious people in their spiritual journey are found.

The bible in Spanish audio (La biblia en audio español) is a modality created so that people with accessibility problems can know the word of God. This way of listening to the bible allows us to analyze it with more clarity, since the interpretation is easier.

Another point in favor of the spoken bible, is that people who cannot read or have lost their vision with the passage of time, can know its content through its audio chapters, the word nourishes the spirit, the bible opens the mind to enlightenment and wisdom to lead a healthy life.

Believing in God strengthens the soul, body and spirit, the word of God is written in the bible, listening to the bible in audio renews the inner forces of the being to move forward, the word gives the necessary strength to face the situations that arise in life.

Listening to the bible is as important as reading it

Currently technology has changed the way of acquiring knowledge by implementing platforms that contain audio books, the audio bible allows us to listen to the scriptures aloud, so we can interpret it better.

The spoken bible allows us to better retain in memory the verses of the book, since, by listening to a topic several times the brain assimilates it better, so the content of the audio bible is more easily remembered.

Listening to the gospels is less tiring than reading them, so you can better analyze the content of the book. The audio bible app in Spanish app biblia en audio en español evokes the time after the death of Christ when the disciples commented on the teachings of the master through oratory.

What is the advantage of listening to the audio bible?

The main advantage is that you can have the bible at hand by downloading it on your device and be able to listen to the word of God whenever you consider it necessary, it is easier to hear the word through the audio bible than to read it.

You can even meditate on the chapter you are listening to by closing your eyes so that you can concentrate better on the analysis of the interpretation of the verse, where you can appreciate the experiences lived by Christians and Jews at the time of Jesus Christ.

There are people who find it difficult to read, so listening to the audio bible is a positive alternative to get closer to God through the knowledge of his word, it also allows them to maintain greater attention and concentration to the speech.

Audio bible, an alternative to get to know the word of God.

The spoken bible gives life to the text, the narration provides greater emotion to the scenario presented in the verses, in addition to reading a text can lose the reader, while with the audiobook the attention to what is said is maintained, improving the interpretation and analysis of the bible.

The audio bible does not replace the study of the word of God but it serves as a key tool to understand what each verse tells us and how to apply it in our daily life, the bible allows us to connect with God through the scriptures.

It is important to listen to the bible in a space where there are no interruptions and you can connect your being with the essence of God, listening to the word is key to achieve the spiritual peace that human beings seek so much.

Conclusion

The spoken bible allows you to fill the gaps that are left when reading the sacred text, because when you listen to its content, you can analyze more deeply the meaning of the verses, the audio bible allows you to nourish the soul.

Having the audio bible downloaded on your mobile device, allows you to connect with God whenever you need it, each verse is interpreted by whoever reads or listens to it, hence, the sacred text becomes a complex book to analyze.

The voice with which they record the spoken bible allows you to experience a feeling of warmth and peace when listening to the word, the dramatization of the spoken bible takes you back to the time when Jesus guided his disciples along the right path to reach God. 

 

The best web design: national product

Galicia web design (in spanish: diseño web Galicia) creates pages with the best features and service features to position them on the web, a company or business must be visible on the network, to achieve this it is necessary to create a functional website with a friendly interface that fits the essence of your company.

A web design must be well structured to achieve success in its positioning, for this reason it is important to have the advice of professional experts who can create an original design.

Currently everything revolves around the digitized world, so it is important for a company or professional to have a website, because through it you have the ability to interact with customers to let them know the products or services offered on the web.

What is the importance of web design in a company?

The design of a web page is important, since it must be attractive for the user to visit it, the Galicia web page design (diseño páginas web Galicia) must also be oriented to the speed of loading the page, which should not exceed 30 seconds to enter.

The quality is another determining factor in the creation of a web, since it influences the success of the positioning and therefore in the increase of sales, the updating of the content is also another important point to make the page attractive.

The design should take into account the organization of the web that is appropriate so that any user interested in visiting it can easily manipulate it, a boring website will not attract the attention of potential customers.

Keys to achieve success in web design in Galicia and throughout Spain

In web design, you should choose bright colors to create an interface with a pleasant visual appearance, the structural organization of the web is a determining factor for the customer to navigate it easily.

The web designer plays a key role in the creation of a page that adapts to the needs of the company but that is friendly for the manipulation by the user, although the content is relevant, the hooking of customers is done with a well-designed page.

Innovation in national web design allows you to create a flexible page, adapted to the new reality of SEO positioning, key factors to increase web traffic to reach a wider audience.

Can I design my own website?

On the internet you can find various programs with which you can design your own website, there are even free platforms on which you can design your website, however, it is important to hire the services of experts in the field of digital design.

…Yes, but better not

The professional advice of a good designer is relevant when it comes to having a website that marks the essence of the company to which the design is made, for a company to get a proper web positioning requires a page that identifies it from the competition. And in our country web designers are among the most competent, creative (and cheap) in the world scene.

Although it is possible to create a website on your own, it is convenient that the design is in the hands of professionals with extensive experience as the designers who are part of the team of the many national design studios.

A web page must be created with the best performance features, so that the user can easily navigate it, the proper structuring is important when organizing the sections of the web.

To conclude, web design focuses on developing digital pages or web applications that allow the interaction of users with the company, the design is based on creating a site easy to manipulate. A good web designer will focus not only on the aesthetics of the page, but also on its usability.

The designer is in charge of keeping the website updated, adapting it to the new design trends, offering the possibility of providing a quality service in the creation of a functional, intuitive, pleasant and well-structured page, continuously in its maintenance.

Conclusion

It is recommended not to make the web design on your own, since you would not have a friendly interface to navigate, and could become a boring website where users do not feel comfortable browsing it.

This is the main reason why the role of the designer is important when creating a website with a professional design that gives seriousness and presence to the company.

 

7 reasons to visit your dentist

Most people will say that going to the dentist is not necessarily at the top of their lists of things they want to do. In reality, the number of people who say they avoid visits due to dental anxiety and fear is around 9% to 15%.

 

The dentist may seem like a scary place, but there are certainly a good amount of perks that should make you want to jump up and schedule an appointment right away. Read on for this list of 7 benefits of regular dental visits that will save you and your teeth.

What happens at a dental visit

 

There are essentially two parts to a visit to a Caceres dentist (dentista Caceres). First, the dentist will examine your entire oral condition, including your teeth, gums and tongue as a routine checkup. They will take x-rays to help get a better idea of what is going on inside your mouth.

 

After this, the dentist will perform a cleaning using various tools, such as scrapers and small mirrors, for a basic dental cleaning of any plaque or tartar buildup. The dentist will provide you with a follow-up plan and ask you to schedule appointments for any additional work that may be necessary, such as a root canal or filling.

1. Prevent future problems

 

You may think that a dentist only works on your teeth, but there are other parts of dental health to consider. One of the benefits of regular dental visits is that the dentist can detect concerns that could develop into bigger problems down the road. For example, if you seem to be developing a small cavity or notice that your gums are not in good shape, you can get treatment right away.

 

Many people experience plaque buildup and gum disease that goes unnoticed because they didn’t see an expert early enough. A dentist can also detect early signs of oral cancer or other major diseases. 

2. Take care of your teeth

 

Sometimes we reach a point where a tooth is so decayed and rotten that it has to be pulled. You only have one set of teeth as an adult, so losing any permanently can be detrimental to your overall oral health.

 

When you lose teeth, different events can occur in your mouth, including your teeth moving on their own. This could cause some discomfort and completely change your smile as you know it. Saving your teeth is one of the best benefits of regular dental visits because it prevents something that is irreversible.

3. Proper dental hygiene education

 

There are many people who are uninformed about the proper ways to manage their dental hygiene. Most people brush their teeth once a day and never floss. This may not sound like a big deal, but it can lead to major problems in the long run.

 

Habits as small as brushing after meals and making sure to floss at least once a day can help fight bacteria in the mouth and promote healthier teeth overall. If you need a more personalized dental hygiene routine, you may want to keep up with your dental checkups so professionals can monitor your oral health. 

4. Help with related problems

 

There are some problems that are related to your dental health that you may not have even considered, such as having trouble sleeping or headaches from grinding your teeth. Being able to address and treat these problems is another benefit of regular dental visits. 

 

Even if at the dental clinic Caceres (clinica dental caceres) can’t give you something to completely stop the problem, he or she will be able to refer you to the right specialist. 

5. Treat bad breath

 

Having chronic bad breath is not just a case of bad morning breath or eating too many onions. A condition called halitosis can occur after repeatedly practicing poor oral hygiene habits. This is not a problem to ignore or try to treat on your own.

 

Be sure to see your dentist so he or she can identify what exactly is causing the odor and how you can fix it. Sometimes it can be a medical condition that needs immediate attention.

6. Give you peace of mind

 

Having dental pain or concerns with your oral health could literally keep you up at night. There are problems that could have very serious consequences if left untreated, such as leaving a decayed tooth in your mouth for too long. That’s why you should visit your dentist regularly.

 

A dentist will be able to keep up with what’s going on in your mouth, help you with the pain and discomfort, and then provide you with a plan for follow-up care. All of these components help you live with more peace of mind and less worry about how serious a problem might be.

7. Have a good smile

 

This may seem like one of the superficial benefits of regular dental visits, but it actually has some deeper advantages that go along with it. Anyone would probably agree that they would love to have a nice smile. Well, visiting the dentist regularly can help achieve that.

 

Getting those pearly whites comes from regular cleanings and following the dentist’s suggestions for taking care of your teeth. It can come from wearing braces or having dental surgery. Whatever the case, a dental professional can point you in the right direction to help you build the best smile and boost your self-esteem.

 

About Outsourcing

As it is well known, within the organizations there are different processes that are developed in different areas of the companies in order to achieve their objectives.

 

The changes that organizations go through are factors that also determine whether or not they achieve their objectives, as well as the resources they use to carry out each of their activities.

 

In current times, globalization has made organizations look for their survival through the search for new markets, cost reduction and competitiveness.

 

SMEs and why not large companies have sought new methods to help them achieve their objectives, making use of the tools at their disposal. Some companies need to focus their attention on the processes that are most important, that is, they invest more resources in the areas they consider most relevant for the development of the organization. This results in some of the areas with little attention being handed over to external agents to take care of the activities in those areas.

 

On the other hand, companies seek to reduce costs and increase the competitiveness levels of some of their processes by looking for external professional personnel to facilitate the execution of the activities and, being agents from outside the organization, the costs generated are lower than those that can be obtained by using internal resources.

 

This technique that allows the entry of external personnel to the organizations to perform the tasks that the company should perform is called «outsourcing».

Definition. 

 

The outsourcing has different definitions are the authors, these can be the following:

 

Outsourcing: is the incorporation to the organization of the competencies that this one has not selected as priority or main, making use of other companies to perform them (Business School, 2002).

Other definitions are as follows:

 

Outsourcing: process by which organizations contract or subcontract all or part of the processes in the production or, in some cases, administrative areas, which were previously performed by the company (Uribe-Echeverria & Rubert Adelantado, 2001).

Outsourcing: economic process in which an organization takes the resources destined to the realization of certain activities and entrusts them to a specialized external company which is in charge of carrying them out (Martínez Gómez, 2012).

Outsourcing is a technique that companies use so that other companies carry out activities that are considered «less» important within the organization, so that the company that hires the services can focus on using its resources in priority activities and at the same time reduce the costs generated by performing these activities using the organization’s own resources.

 

Outsourcing.

 

Today’s managers in charge of their own organizations are faced with a great number of changes, which include:

 

Globalizing activities.

Grow without having to use more resources (more capital).

  • Reducing costs.
  • Understanding consumer tastes.
  • The need to respond to threats and, above all, to opportunities.
  • The aging workforce

Outsourcing, known in Spanish as subcontracting, outsourcing or externalization (although the latter differ slightly from the concept of outsourcing), is a technique that organizations use to get external suppliers, which perform activities that the company itself performed internally or, failing that, serve as a plus to internal processes.

 

Maintaining the main functions within the organization using the company’s own resources and hiring external services to perform support or secondary activities is known as strategic outsourcing, which is considered a means to maintain and increase competitiveness. A very simple example can be the following: a company A makes use of the services or inputs of a company B, whether it is foreign, national, related or unrelated to company A.

 

What identifies outsourcing as a practice performed by an organization is that a third party performs one or more functions that were previously owned by the organization, which for various reasons decides to stop performing them, so it transfers them to a third party.

 

The construction of the word outsourcing is made up of the English words out and source. Hence, external sources are used, in this case, companies outside the outsourcing organization.

 

Many people confuse outsourcing with the contracting of services from an external company, where in the first one there are exchanges of information, coordination and above all trust, even assignments of corporate responsibility are made even if these are minimal; on the other hand in the contracting the company that hires the service only determines which is the work that it wants to acquire and the contractor is limited to fulfill it in time and form.

 

There are several areas where outsourcing is put into practice, these can be: human resources, computer services, accounting, warehouse management or technical support which often includes call centers, likewise, companies that perform engineering and manufacturing activities can also be subcontracted.

 

It is correct to mention that outsourcing is applied in activities that are not the main ones for the organization that outsources to another company.

 

As an example, the so-called call centers are places where telephone assistance is provided to customers in a personal manner. This assistance can be provided from countries outside the customer’s country of origin, such as India, Pakistan, Uruguay, Philippines, among others. The outsourcing of this external service provides a competitive advantage to the organization, which seeks to reduce costs in the area of customer service, since it is much cheaper than having an internal department that is responsible for this activity (Bohon Devars, 2009).

 

Reasons for outsourcing.

 

In the past, many considered outsourcing Philippines as the only way to reduce costs, but nowadays it has proven to be a very useful technique for the growth of companies for reasons such as the following:

 

  • Reduction and control of expenses (in certain cases it is cheaper to outsource certain activities to third parties than to have the organization itself perform them).
  • Concentration on the areas of the organization that serve as pillars for the same, which are its raison d’être, and also to properly dispose of the company’s capital, due to the reduction of this, in functions not related to the raison d’être of the company.
  • To have personnel with a high professional capacity.
  • To allocate most of the resources and investments to the main objectives of the organization.
  • Greater efficiency.
  • Instant access to technology.
  • Improve response times.
  • Transfer the challenge of technological innovation and evolution to the service provider (Besil Bardawil, Pliego Rosique, & Madrigal Hinojosa, 2013).
  • The aforementioned reasons allow the organization to concentrate mostly on the business issues that it considers and are of importance, while the outsourced company performs the activities that are somewhat more secondary.